• Location: Cambridge, MA
• Type: Temporary
• Job #4995

Associate Scientist, Process Sciences

Start: 03/24/2020
End: 09/24/2020

Duties:

The successful candidate will be a part of the Process Sciences group, responsible for the process development of oligo manufacturing, and the in-house non-GMP manufacture of modified oligonucleotides and siRNAs.

Summary of Key Responsibilities

Assistance in these activities is required:

• oligonucleotide synthesis activities, method development, optimization and scale-up 
• downstream production activities, as well as method development and optimization• execution of in-process analytical tests
• creation, review, and usage of SOPs and batch records employed for the in-house non-GMP oligonucleotide 

Skills:

• Experience in oligonucleotide including phosphoramidite chemistry, chromatography, ultrafiltration etc. 
• Experience in analytical techniques (pH, osmolality, conductivity measurement, HPLC, LC-MS etc.), or related hands-on experience, is preferred.
• Experience in record-keeping and excellent laboratory documentation practice, are required.
• Strong commitment to preserving a high laboratory and scientific standard; maintaining a safe, clean, and orderly laboratory work environment; assisting in routine lab and equipment maintenance; assisting with vendor contract and requisitions.
• Excellent written and oral communication skills, good organization skills, and multi-tasking abilities are required. The successful candidate must be responsible and proactive individual who is able to work as an individual contributor in a highly dynamic team environment with aggressive timelines. 

Education:

• Bachelor's or Master's degree in Chemistry, Biochemistry, or a related scientific field
• 1-4 years of work experience, preferably in an industrial setting.

Keywords

CHROMATOGRAPHY
DOCUMENTATION
EQUIPMENT MAINTENANCE
EXCELLENT WRITTEN
CHEMISTRY

Additional Skills:

HPLC
LABORATORY
MAINTENANCE
ORGANIZATION SKILLS
BATCH RECORDS
BIOCHEMISTRY
GMP
OPTIMIZATION
PROCESS DEVELOPMENT
SELF MOTIVATED
SOPS

Languages:
English
        Read
        Write
        Speak

Minimum Degree Required: Bachelor's Degree
Patents: No
Publications: No
Veteran Status: No
# of Positions: 1

Location:
Cambridge, MA

Start Date: 03/24/2020
Estimated End Date: 09/24/2020
Hours Per Week: 40.00
Hours Per Day: 8.00

All qualified candidates are urged to submit a Word resume and cover letter in (2) Word documents for immediate and assured response.